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Paranasal sinuses are a group of four paired air-filled spaces that surround the . The are located under the ; the are above the eyes; the are between the eyes and the are behind the eyes. The sinuses are named for the in which they are located. Their role is disputed.


Structure
Humans possess four pairs of paranasal sinuses, divided into subgroups that are named according to the within which the sinuses lie. They are all innervated by branches of the (CN V).

The paranasal sinuses are lined with respiratory epithelium (ciliated pseudostratified columnar epithelium).


Functions
One known function of the paranasal sinuses is the production of , which also functions as a facilitator of oxygen uptake.


Development
Paranasal sinuses form developmentally through excavation of bone by air-filled sacs (pneumatic diverticula) from the . This process begins prenatally (intrauterine life), and it continues through the course of an organism's lifetime.

The results of experimental studies suggest that the natural ventilation rate of a sinus with a single (opening) is extremely slow. Such limited ventilation may be protective for the sinus, as it would help prevent drying of its mucosal surface and maintain a near-sterile environment with high concentrations and minimal access. Thus composition of gas content in the maxillary sinus is similar to , with high carbon dioxide and lower levels compared to breathing air.

At birth, only the and the are developed but not yet pneumatized; only by the age of seven are they fully aerated. The appears at the age of three, and the first appear at the age of six, and fully develop during adulthood.

===CT scans, radiographs (x-ray) and other illustrations===


Clinical significance

Inflammation
The paranasal sinuses are joined to the via small orifices called . These become blocked easily by allergic inflammation, or by swelling in the nasal lining that occurs with a . If this happens, normal drainage of within the sinuses is disrupted, and may occur. Because the maxillary posterior teeth are close to the maxillary sinus, this can also cause clinical problems if any disease processes are present, such as an infection in any of these teeth. These clinical problems can include secondary sinusitis, the inflammation of the sinuses from another source such as an infection of the adjacent teeth.Illustrated Anatomy of the Head and Neck, Fehrenbach and Herring, Elsevier, 2012, p. 68

These conditions may be treated with drugs such as , which cause in the sinuses; reducing inflammation; by traditional techniques of ; or by .


Cancer
Malignancies of the paranasal sinuses comprise approximately 0.2% of all malignancies. About 80% of these malignancies arise in the maxillary sinus. Men are much more often affected than women. They most often occur in the age group between 40 and 70 years. are more frequent than . Metastases are rare. of the sphenoid and frontal sinuses are extremely rare.


Etymology
Sinus is a word meaning a fold, curve, or bay. Compare .


Other animals
Paranasal sinuses occur in many other animals, including most , , and . They have also been discovered in non-avian . The bones occupied by sinuses vary with species.

==Illustrations==


See also

External links
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